The study is an analysis of processing methods, marketing channels, and profitability determinants of selected cassava products in Kogi state, Nigeria. The study was carried out in Kogi East senatorial District of the state. A multi-stage sampling technique was employed in the selection of 120 respondents from whom information were collected and analyzed. The data used for the study were collected using structured questionnaire and analyzed using descriptive statistics and profit function analysis. The study showed that there are three processing methods and three marketing channels for each of the cassava products selected. The study also showed that the variable costs and fixed costs were both significant in profit determination. The study concluded that processing and marketing activities of cassava products are prominent are profitable in the study area. It was recommended that the capital base of the respondents be boosted so that they can use modern processing and packaging techniques.